Professor Ayman Sadek Ahmed El-Faham
Position : Faculty Member
Email : ayman.a@dau.edu.sa
Phone : 011-4949376
Fax :
Summary of his biography :
Prof. Ayman El-Faham focuses on the synthesis and characterization of peptides, peptide coupling reagents, green chemistry, medicinal chemistry, and biologically active small compounds based triazine moiety. He has more than 290 publications in highly cited journal, 14 US-patent. He received the B.Sc. degree in Chemistry in 1980 and M.Sc. in 1985 in Physical Organic Chemistry, from Faculty of Science, University of Alexandria, Egypt. In 1991 he received his Ph.D degree in organic chemistry as a joint project between the University of Massachusetts, Amherst, MA, U. S. A. and the University of Alexandria under the supervision of Prof. L. A. Carpino, where he worked on the synthesis of new protecting groups for both solution and solid phase peptide synthesis. In addition, he involved in the development of new coupling reagents based on 1-hydroxy-7-azabenzotriazole. He continued working on these new coupling reagents as a postdoctoral work at the University of Massachusetts in Prof. Carpino’s Lab (1992-1999). He shared many patents in peptide field. In 1999 he received the University of Alexandria award in Chemistry. He nominated to submit a proposal for Noble prize in 2003. Also, he has collaborated with Barcelona Science Park, Barcelona University, Spain from 2006 to present with Prof. Fernando Albericio in the development of a new family of immonium/uronium type coupling reagents and drug design based Triazine moiety. In 2000-2004, he worked as the Head of the Chemistry Department, Beirut Arab University, Lebanon. In 2004-2008, he worked as the Direct Manager of both the NMR Lab and the Central Lab at the Faculty of Science, Alexandria University, Egypt. 2008-2010, he worked at King Saud University, as a Professor of Organic Chemistry, College of Science, Chemistry Department, Saudi Arabia. In 2010, he received the D.Sc. degree in Peptide Synthesis. In 2010 he received the University of Alexandria a Medal award in Chemistry for scientific publication. 2010-2011, he worked as a Vice Dean of Community Service and Environment Development, in 2012 he received Award of Excellence in Scientific Publishing from Quality Authority (CIQAP) Egypt 2012. From 2011 to 2021, he worked at King Saud University, as a Professor of Organic Chemistry, College of Science, Chemistry Department, Saudi Arabia. He is Emeritus Professor of Organic and Peptide Chemistry, Faculty of Science, Alexandria. He recorded as top 2% Scientist around the world according to the published data by Stanford, five years in rolled 2024,2023, 2022, 2021, 2020. Currently, he is a Professor at College of Medicine, Dar Al Uloom University, Riyadh, Saudi Arabia. In addition he is the head of the Center of Entrepreneurship & Innovation and Knowlege Transfer at DAU.
| Title | Date | Major | Organization |
|---|---|---|---|
| BSc | 1980 | Chemistry | Alexandria University |
| MSc | 1985 | Chemistry | |
| PhD | 1991 | Chemistry | Alexandria University |
| DSc | 2010 | Chemistry | Alexandria University |
| Title | Organization | Date From | Date To |
|---|---|---|---|
| Professor | Alexandria University | 27-11-2001 | 30-08-2024 |
| Associate Professor | Alexandria University | 29-10-1996 | 26-11-2001 |
| Assistant Professor | Alexandria University | 24-09-1991 | 28-10-1996 |
| Assistant Lecture | Alexandria University | 25-11-1985 | 23-09-1991 |
| Demonstrator | Alexandria University | 07-10-1980 | 24-11-1985 |
| Professor | King Saud University | 01-09-2008 | 30-07-2010 |
| Professor | King Saud University | 01-09-2011 | 18-07-2021 |
| Professor, Head of Chemistry Department | Beirut Arab University, Faculty of Science, Lebanon | 01-09-2000 | 30-07-2004 |
| Vice-Dean for Community Development & Environmental Affairs, University of Alexandria, Faculty of Science | Alexandria University | 23-09-2010 | 08-10-2011 |
| Post-Doctoral Research Associate | University of Massachusetts, UMASS, Amherst | 01-09-1992 | 30-08-1994 |
| Post-Doctoral Research Associate | University of Massachusetts, UMASS, Amherst | 01-09-1996 | 30-08-1998 |
| Visiting Research Professor | University of Barcelona, Barcelona Science Park | 01-07-2006 | 30-08-2011 |
| Title | Publish Date | Journal |
|---|---|---|
| Synthesis, X-ray Crystal Structure and Antimicrobial Activity of Unexpected Trinuclear Cu(II) Complex from s-Triazine-Based Di-Compartmental Ligand via Self-Assembly | 2019 | Crystals 2019, 9, 661; doi:10.3390/cryst9120661 |
| A Simple, Efficient, and Eco-Friendly Method for the Preparation of 3-Substituted-2,3-dihydroquinazolin-4(1H)-one Derivatives | 2019 | Molecules 2019, 24, 4052; doi:10.3390/molecules24224052 |
| Investigating Triorthogonal Chemoselectivity. Effect of Azide Substitution on the Triazine Core | 2019 | Org. Lett. 2019, 21, 2459−2463; doi: 10.1021/acs.orglett.9b02878 |
| γ-Valerolactone (GVL): An eco-friendly anchoring solvent for solid-phase peptide synthesis | 2019 | Tetrahedron Letters, 2019, 60, 151058; doi: 10.1016/j.tetlet.2019.151058 |
| Bis-pyrazolyl-s-triazine Ni(II) pincer complexes as selective gram positive antibacterial agents; synthesis, structural and antimicrobial studies | 2019 | J. Mol. Str. 2019, 1195, 315-322; doi: 10.1016/j.molstruc.2019.05.103 |
| Physico Chemical and Biological Evaluation of PLCL/SF Nanofibers Loaded with Oregano Essential Oil | 2019 | Pharmaceutics 2019, 11, 386 (1-18); doi:10.3390/pharmaceutics11080386 |
| Pseudo-Wang Handle for the Preparation of Fully Protected Peptides. Synthesis of Liraglutide by Fragment Condensation | 2019 | Org. Lett. 2019, 21, 2459−2463; doi: 10.1021/acs.orglett.9b00813 |
| Optimized Stepwise Synthesis of the API Liraglutide Using BAL Resin and Pseudoprolines | 2019 | ACS Omega 2019, 4, 8674−8680; doi: 10.1021/acsomega.9b00974. |
| Synthesis, X-ray structure and DFT studies of five- and eight-coordinated Cd(II) complexes with s-triazine N-pincer chelate | 2019 | J. Coord. Chem., 2019, 72, 1621-1636; doi: 10.1080/00958972.2019.1608360. |
| Cu(II)-promoted cyclization of Hydrazonophthalazine to triazolophthalazine; Synthesis and structure diversity of six novel copper(II) complexes | 2019 | Applied Organometallic Chemistry; 2019; e4992; doi.org/10.1002/aoc.4992 |
| Cu(II)-promoted cyclization of Hydrazonophthalazine to triazolophthalazine; Synthesis and structure diversity of six novel copper(II) complexes | 2019 | Applied Organometallic Chemistry; 2019; e4992; doi.org/10.1002/aoc.4992 |
| Synthesis, Molecular and Supramolecular Structures of New Cd(II) Pincer-Type Complexes with s- Triazine Core Ligand | 2019 | . Crystals 2019, 9, 226 (1-16); doi:10.3390/cryst9050226. |
| Bypassing Osmotic Shock Dilemma in a Polystyrene Resin Using the Green Solvent Cyclopentyl methyl Ether (CPME): A Morphological Perspective | 2019 | Polymers 2019, 11, 874 (1-13) ; doi:10.3390/polym11050874. |
| Synthesis, X-Ray Crystal Structures, and Preliminary Anti-proliferative Activities of News-Triazine-hydroxybenzylidene Hydrazone Derivatives | 2019 | Journal of Chemistry 2019, Volume 2019, Article ID 9403908, 10 pages ; doi: 10.1155/2019/9403908 |
| Efficient Route for Synthesis of Enamines from 1,3-Alkyl-2-Thioxodihydropyrimidine-4,6(1H,5H)-dione Enols | 2019 | Lett. in Org. Chem., 2019, 16, 538-540; doi: 10.2174/1570178616666190409145118 |
| Synthesis and structural DFT studies of Ni(II) and Co(II) complexes with s-triazine-based di-compartmental ligand | 2019 | Polyhedron 2019, 165, 162–170; doi: 10.1016/j.poly.2019.03.024 |
| Synthesis, molecular structure and DFT studies of two heteroleptic nickel(II) s-triazine pincer type complexes | 2019 | J. Mol. Str., 2019, 1185, 461-468; doi: 10.1016/j.molstruc.2019.02.089 |
| Design and synthesis of mono-and di-pyrazolyl-s-triazine derivatives, their anticancer profile in human cancer cell lines, and in vivo toxicity in zebrafish embryos | 2019 | Bioorg. Chem., 2019, 87, 457–464; doi: 10.1016/j.bioorg.2019.03.063 |
| Green Transformation of Solid-Phase Peptide Synthesis | 2019 | ACS Sustainable Chem. Eng., 2019, 7, 3671−3683. doi: 10.1021/acssuschemeng.8b06520. |
| Synthesis and structure diversity of high coordination number Cd(II) complexes of large s-triazine bis-Schiff base pincer chelate | 2019 | Inorganica Chimica Acta 2019, 488, 131–140; doi: 10.1016/j.ica.2019.01.018. |
| Hunt Bacteria through an Intriguing Cyclic Peptide | 2019 | ChemMedChem, 2019, 14, 24 – 5; doi: 10.1002/cmdc.201800597. |
| A Facile and Eco-Friendly Method for the Synthesis of Sulfonamide and Sulfonate Carboxylic Acid Derivatives—X-ray Structure, Hirshfeld Analysis and Spectroscopic Characterizations | 2019 | Crystals 2019, 9, 35; doi:10.3390/cryst9010035. |
| Evaluation of clay-ionene nanocomposite carriers for controlled drug delivery: Synthesis, in vitro drug release, and kinetics | 2019 | Mater. Chem. Phy., 2019, 225, 122–132; dio: 10.1016/j.matchemphys.2018.12.054 |
| Eco-friendly method for silver nanoparticles immobilized decorated silica: Synthesis & characterization and preliminary antibacterial activity | 2019 | J. Taiwan Inst. Chem. Eng., 2019, 95,423-331; doi.org/10.1016/j.jtice.2018.07.020 |
| . Modified Epoxy with Chitosan Triazine Dihydrazide Derivatives for Mechanical and Corrosion Protection of Steel | 2020 | Coatings 2020, 10, 1256; doi:10.3390/coatings10121256 w. |
| Fe(III) Complexes Based on Mono- and Bispyrazolyl-s-triazine Ligands: Synthesis, Molecular Structure, Hirshfeld, and Antimicrobial Evaluations | 2020 | Molecules 2020, 25, 5750; doi:10.3390/molecules25235750 |
| Ultrasonically Assisted N Cyanoacylation and Synthesis of Alkyl(4- (3-cyano-4,6-dimethyl-2-oxopyridin-1(2H) yl)benzoyl)amino Acid Ester Derivatives. | 2020 | . ACS Omega 2020, 5(47), 30671-30678; doi: 10.1021/acsomega.0c04730 |
| Novel 4,6-disubstituted s-Triazin-2-yl Amino Acid 3 Derivatives as Promising Antifungal Agents | 2020 | J. Fungi 2020, 6, 237; doi:10.3390/jof6040237 |
| Synthesis, X-ray Structure, Hirshfeld Analysis of Biologically Active Mn(II) Pincer Complexes Based on s-Triazine Ligands | 2020 | Crystals 2020, 10, 931; doi:10.3390/cryst10100931. |
| Exploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups | 2020 | Bioorganic Chemistry 2020, 104, 104334; doi: 10.1016/j.bioorg.2020.104334 |
| OxymaPure Coupling Reagents: Beyond Solid-Phase Peptide Synthesis | 2020 | Synthesis 2020, 52, 3189-3210; doi: 10.1055/s-0040-1706296. |
| 1,3,5-Triazine as core for the preparation of dendrons | 2020 | Arkivoc 2020, part iii, doi: 10.24820/ark.5550190.p011.245 |
| Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives | 2020 | Molecules 2020, 25, 4065; doi:10.3390/molecules25184065 |
| Barbiturate- and Thiobarbituarte-Based s‑Triazine Hydrazone Derivatives with Promising Antiproliferative Activities | 2020 | ACS Omega 2020, 5, 15805−15811; doi.org/10.1021/acsomega.0c00468 |
| Synthesis, structure and in vitro anticancer activity of Pd(II) complexes of mono- and bis-pyrazolyl-s-triazine ligands | 2020 | Polyhedron 2020, 187,114665; doi.org/10.1016/j.poly.2020.114665. |
| Chitosan-s-triazinyl-bis(2-aminomethylpyridine) and chitosan-s-triazinylbis(8-oxyquinoline) derivatives: New reagents for silver nanoparticles preparation and their effect of antimicrobial evaluation | 2020 | Journal of Chemistry, 2020, 2020, Article ID 9590120, 8 pages; doi: 10.1155/2020/9590120 |
| Molecular and supramolecular structures of self-assembled Cu(II) and Co(II) complexes with 4,4’-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5- triazine-2,4-diyl]dimorpholine ligand | 2020 | J. Mol. Str. 2020, 1219, 128584; doi:10.1016/j.molstruc.2020.128584 |
| Synthesis and Characterization of New Series of 1,3-5-Triazine Hydrazone Derivatives with Promising Antiproliferative Activity | 2020 | Molecules 2020, 25, 2708; doi:10.3390/molecules25112708 |
| Crystal Structure and Theoretical Investigation of Thiobarbituric Acid Derivatives as Nonlinear Optical (NLO) Materials | 2020 | Crystals 2020, 10, 442; doi:10.3390/cryst10060442 |
| Enamine Barbiturates and Thiobarbiturates as a New Class of Bacterial Urease Inhibitors | 2020 | Appl. Sci. 2020, 10(10), 3523; doi:10.3390/app10103523 |
| Synthesis, X-ray structure, Hirshfeld analysis, and DFT studies of a new Pd(II) complex with an anionic s-triazine NNO donor ligand | 2020 | J.Mol. Str. 2020, 1217, 128463, doi:10.1016/j.molstruc.2020.128463 |
| Novel one-dimensional polymeric Cu(II) complexes via Cu(II)-assisted hydrolysis of the 2,4-bis(3,5-dimethyl-1Hpyrazol- 1-yl)-6-methoxy-1,3,5-triazine pincer ligand: Synthesis, structure, and antimicrobial activities | 2020 | Appl Organomet Chem. 2020; e5941; DOI: 10.1002/aoc.5941 |
| Syntheses, structure, Hirshfeld analysis and antimicrobial activity of four new Co(II) complexes with s-triazine-based pincer ligand | 2020 | Inorganica Chimica Acta. 2020, 510, 119753, doi:10.1016/j.ica.2020.119753 |
| Synthesis, Characterization of sym-2,4,6-trisubstituted-s-Triazine Derivatives and Their Effects on Flame Retardancy of Polypropylene Composites | 2020 | Processes 2020, 8(5), 581; doi:10.3390/pr8050581 |
| Multi-Functional Cardanol Triazine Schiff Base Polyimine Additives for Self-Healing and Super-Hydrophobic Epoxy of Steel Coating | 2020 | Coatings 2020, 10, 327; doi:10.3390/coatings10040327 |
| Carpino's protecting groups, beyond the Boc and the Fmoc | 2020 | Pept Sci. 2020;e24164. Doi:10.1002/pep2.24164 |
| Functionalization of Silica with Triazine Hydrazide to Improve Corrosion Protection and Interfacial Adhesion Properties of Epoxy Coating and Steel Substrate | 2020 | Coatings 2020, 10, 351; doi:10.3390/coatings10040351. |
| Simple approaches for the synthesis of AgNPs in solution and solid phase using modified methoxypolyethylene glycol and evaluation of their antimicrobial activity | 2020 | International Journal of Nanomedicine, 2020, 15, 2353–2362; doi: 10.2147/IJN.S244678. |
| Synthesis, structure and biological activity of zinc(II) pincer complexes with 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine | 2020 | Inorganica Chimica Acta 2020, 508, 119627; doi: 10.1016/j.ica.2020.119627. |
| Mono- and penta-nuclear self-assembled silver(I) complexes of pyrazolyl s-triazine ligand; synthesis, structure and antimicrobial studies | 2020 | Appl Organometal Chem. 2020;34:e5603.; Doi: 10.1002/aoc.5603 |
| Protocol for synthesis of di- and tri-substituted s-triazine derivatives | 2020 | MethodsX, 2020, 7, 100825; doi: 0.1016/j.bioorg.2019.103397 |
| Microwave-Assisted Synthesis of Cross-Linked Co-poly(itaconic anhydride-methyl methacrylate): The Effects of the Molar Ratio and Cross-Linking Agent on the Thermal Stability | 2020 | Int. J. Polym. Sci., 2020; Vol. 2020, Article ID 9706106, 11 pages; doi:10.1155/2020/9706106 |
| Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity | 2020 | ” J. Enzy. Inhib. Med. Chem., 2020; 35:1, 692-701, DOI: 10.1080/14756366.2020.1737045. |
| Synthesis, crystal structure, DFT and biological activity of E-pyrene-1-carbaldehyde oxime and E-2-naphthaldehyde oxime | 2020 | J. Mol. Str., 2020, 1207, 127848; doi: 10.1016/j.molstruc.2020.127848. |
| Phenol as a Modulator in the Chemical Reactivity of 2,4,6-Trichloro-1,3,5-triazine: Rules of the Game II | 2020 | . Aust. J. Chem. 2020, 1-5, doi.org/10.1071/CH19524 |
| A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors | 2020 | J. ENZY. INHIB. MED. CHEM., 2020, 35(1), 549–554; doi: 10.1080/14756366.2020.1715388 |
| Synthesis, crystal structure, evaluation of urease inhibition potential and the docking studies of cobalt(III) complex based on barbituric acid Schiff base ligand | 2020 | Inorganic Chimica Acta, 2020, 503, 119405; doi.org/10.1016/j.ica.2019.119405 |
| Synthesis, characterization, thermal stability and kinetics of thermal degradation of novel polymers based-s-triazine Schiff base | 2020 | Journal of Polymer Research 2020, 27:10, 1-11; doi.org/10.1007/s10965-019-1961-8 |
| Di- and tri-substituted s-triazine derivatives: Synthesis, characterization, anticancer activity in human breast-cancer cell lines, and developmental toxicity in zebrafish embryos | 2020 | Bioorg. Chem. 94 (2020) 103397 doi: 10.1016/j.bioorg.2019.103397 |
| Three Multi-Components Reaction: Synthesis and X-Ray Single-Crystal of Hydroacridinone-Based Hydrazino-S-Triazine Derivative as a New Class of Urease Inhibitor | 2020 | Crystals 2020, 10, 14; doi:10.3390/cryst10010014. |
| Synthesis and Antimicrobial Activity of a New Series of Thiazolidine-2,4-diones Carboxamide and Amino Acid Derivatives | 2020 | Molecules 2020, 25, 105; doi:10.3390/molecules25010105 |
| Synthesis, and Molecular Structure Investigations of a New s-Triazine Derivatives Incorporating Pyrazole/Piperidine/ Aniline Moieties | 2021 | Crystals 2021, 11, 1500; doi:10.3390/cryst11121500 |
| Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole-Engrafted Rhodanine Analogs | 2021 | Molecules 2021, 26, 7276; doi. 10.3390/molecules262372. |
| Synthesis, X-ray Structure, Conformational Analysis, and DFT Studies of a Giant s-Triazine bis-Schiff Base | 2021 | Crystals 2021, 11, 1418; doi: 10.3390/cryst11111418 |
| Preparation of Multifunctional Plasma Cured Cellulose Fibers Coated with Photo-Induced Nanocomposite toward Self-Cleaning and Antibacterial Textiles | 2021 | Polymers 2021, 13, 3664; doi.org/10.3390/polym13213664 |
| Minimizing Side-Reactions During Amide Formation using DIC and OxymaPure in Solid-Phase Peptide Synthesis | 2021 | Tetrahedron Lett. 2021, 153462; doi: 10.1016/j.tetlet.2021.153462. |
| Amide Formation: Choosing the Safer Carbodiimide in Combination with OxymaPure to Avoid HCN Release | 2021 | Org. Lett. 2021; 23, 6900−6904; doi:10.1021/acs.orglett.1c02466 |
| Synthesis, characterization and comparative thermal degradation kinetics of s‑Triazine based polymers | 2021 | J. Poly. Res. 2021, 28(304); doi: 10.1007/s10965-021-02667-y. |
| Molecular and Supramolecular Structures of Cd(II) Complexes with Hydralazine-Based Ligands; A New Example for Cyclization of Hydrazonophthalazine to Triazolophthalazine. | 2021 | Crystals 2021, 11, 823; doi: 10.3390/cryst11070823. |
| A Novel Centrosymmetric Fe(III) Complex with Anionic Bis-pyrazolyl-s-triazine Ligand; Synthesis, Structural Investigations and Antimicrobial Evaluations | 2021 | Symmetry 2021, 13, 1247; doi: 10.3390/sym13071247 |
| Latest Advances on Synthesis, Purification, and Characterization of Peptides and Their Applications | 2021 | Appl. Sci. 2021, 11, 5593; doi:10.3390/app11125593. |
| Syntheses and Structural Investigations of Penta-Coordinated Co(II) Complexes with Bis-Pyrazolo-S- Triazine Pincer Ligands, and Evaluation of Their Antimicrobial and Antioxidant Activities | 2021 | Molecules 2021, 26, 3633; doi: 10.3390/molecules26123633. |
| s-Triazine Pincer Ligands: Synthesis of their Metal Complexes, Coordination Behavior, and Applications | 2021 | Applied Organometallic Chemistry. 2021, 35:e6317; doi: 10.1002/aoc.6317. |
| Scope and Limitations of Barbituric and Thiobarbituric Amino Acid Derivatives as Protecting Groups for Solid-Phase Peptide Synthesis: Towards a Green Protecting Group | 2021 | ChemistrySelect., 2021, 6, 6626–6630; doi: 10.1002/slct.202101539. |
| Preparation and Characterization of Nanofibrous Scaffolds of Ag/Vanadate Hydroxyapatite Encapsulated into Polycaprolactone: Morphology, Mechanical, and In Vitro Cells Adhesion | 2021 | Polymers 2021, 13, 1327; doi. 10.3390/polym13081327 |
| The Antiproliferative and Apoptotic Effect of a Novel Synthesized S-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos | 2021 | Molecules 2021, 26, doi: 10.3390/molecules26041170. |
| Enhancing the Antifungal Activity of Griseofulvin by Incorporation a Green Biopolymer‐Based Nanocomposite | 2021 | Polymers, 2021, 13, 542; doi: 10.3390/polym13040542 |
| Synthesis, Structure and In Vitro Anticancer Activity of Pd(II) Complex of Pyrazolyl-s-Triazine Ligand; A New Example of Metal-Mediated Hydrolysis of s-Triazine Pincer Ligand | 2021 | Crystals, 2021, 11, 119; doi: 10.3390/cryst11020119. |
| A Privileged Structure for Drug Discovery and Bioconjugation | 2021 | Molecules, 2021, 26, 864; doi: 10.3390/molecules26040864. |
| In situ preparation of composites based on trishydrazino-s-triazine (1,4-/1,3-) benzene dicarboxyaldehyde with reduced graphene oxide and their electrical conductivity performance | 2021 | J. Mater. Res. Technol. 2021, 10, 1280-1290; doi: 10.1016/j.jmrt.2020.12.075. |
| Synthesis and X-ray Structure Combined with Hirshfeld and AIM Studies on a New Trinuclear Zn(II)-Azido Complex with s-Triazine Pincer Ligand | 2022 | Crystals 2022, 12, 1786; doi: 10.3390/cryst12121786. |
| Pyrazolyl-s-Triazine with Indole Motif as a Novel of Epidermal Growth Factor Receptor/ Cyclin-Dependent Kinase 2 Dual Inhibitors | 2022 | Fornt. Chem, 2022, 10:1078163; doi: 10.3389/fchem.2022.1078163. |
| Synthesis, Molecular and Supramolecular Structures of Symmetric Dinuclear Cd(II) Azido Complex with bis-Pyrazolyl s-Triazine Pincer Ligand | 2022 | Symmetry 2022, 14, 2409. doi.org/10.3390/sym14112409 |
| [3 + 2] Cycloadditions in Asymmetric Synthesis of Spirooxindole Hybrids Linked to Triazole and Ferrocene Units: X-ray Crystal Structure and MEDT Study of the Reaction Mechanism. | 2022 | Symmetry 2022, 14, 2071; doi 10.3390/sym14102071 |
| Synthesis and Solid-State X-Ray Structure of the Mononuclear Palladium(II) Complex Based on 1,2,3-Triazole Ligand | 2022 | Crystals 2022, 12, 1335; doi:10.3390/cryst12101335 |
| tert-Butylethylcarbodiimide as an Efficient Substitute for Diisopropylcarbodiimide in Solid-Phase Peptide Synthesis: Understanding the Side Reaction of Carbodiimides with OxymaPure | 2022 | Org. Process Res. Dev. 2022, 26, 2894−2899; doi: 10.1021/acs.oprd.2c00220. |
| Syntheses, X-ray structure and biological studies of binuclear μ-oxo diiron complexes with s-triazine pincer ligand | 2022 | Inorganica Chimica Acta. 2022, 543, 121196; doi: 10.1016/j.ica.2022.121196 |
| Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades | 2022 | Pharmaceutics 2022, 14, 1558; doi:10.3390/pharmaceutics14081558 |
| Synthesis and Antiproliferative Activity of a New Series of Monoand Bis(dimethylpyrazolyl) s triazine Derivatives Targeting EGFR/ PI3K/AKT/mTOR Signaling Cascades | 2022 | ACS Omega, 2022, 7(28), 24858–24870, doi: 10.1021/acsomega.2c03079. |
| Synthesis, in vitro and in cell study of a new spirooxindoles based N-alkylated maleimides targeting HER2/3 signaling pathway | 2022 | POLYCYCLIC AROMATIC COMPOUNDS, 2022, 1-26, doi: 10.1080/10406638.2022.2101486 |
| . X-ray Structure Analyses and Biological Evaluations of a New Cd(II) Complex with S-Triazine Based Ligand | 2022 | Crystals 2022, 12, 861. doi.10.3390/cryst12060861. |
| Synthesis, Structure and Biological Evaluations of Zn(II) Pincer Complexes Based on S-Triazine Type Chelator | 2022 | Molecules 2022, 27, 3625; doi. 10.3390/molecules27113625. |
| Co (II) Complexes Based on the Bis-Pyrazol-S-Triazine Pincer Ligand: Synthesis, X-ray Structure Studies, and Cytotoxic Evaluation | 2022 | Crystals 2022, 12, 741; doi: 10.3390/cryst12050741 |
| Synthesis, X-ray structure and biological studies of new self-assembled Cu(II) complexes derived from s-triazine Schiff base ligand | 2022 | Molecules 2022, 27, 2989; doi. 10.3390/molecules27092989 |
| A New Pt(II) Complex with Anionic s-Triazine Based NNO-Donor Ligand: Synthesis, X-ray Structure, Hirshfeld Analysis and DFT Studies | 2022 | Molecules 2022, 27, 1628; doi.10.3390/molecules27051628 |
| Synthesis of New S-Triazine Bishydrazino and Bishydrazido-Based Polymers and Their Application in Flame-Retardant Polypropylene Composites | 2022 | Polymers 2022, 14, 784. doi. 10.3390/polym14040784 |
| Understanding OxymaPure as a Peptide Coupling Additive: A Guide to New Oxyma Derivatives | 2022 | ACS Omega, 2022, 7, 6007−6023; doi. 10.1021/acsomega.1c06342 A. |
| Synthesis, molecular and supramolecular structure aspects and biological evaluations of a novel [Ag2(phthalazine)(NO3)2]n 3D coordination polymer | 2022 | J. Mol. Str. 2022, 1257, 132592; doi.10.1016/j.molstruc.2022.132592. |
| Synthesis, structure, X-ray photoelectron spectroscopy (XPS), and antimicrobial, anticancer, and antioxidant activities of Co (III) complexes based on the antihypertensive hydralazine | 2022 | Appl Organomet Chem. 2022; e6565; doi: 10.1002/aoc.6565. |
| Synthesis and Characterizations of Novel Isatin-s-Triazine Hydrazone Derivatives; X-ray Structure, Hirshfeld Analysis and DFT Calculations | 2023 | Crystals 2023, 13, 305; doi. 10.3390/cryst13020305. |
| Cytotoxicity and Apoptosis-Induction in MCF-7 Cells for New Pd(II) Complex Based on s-Triazine Ligand: Synthesis, Single Crystal X-Ray Diffraction Analysis and Structural Investigations | 2023 | Crystals 2023, 13, 1472; doi.10.3390/cryst13101472. |
| . Synthesis and X-ray Structure Analysis of the Polymeric [Ag2(4-Amino-4H-1,2,4-triazole)2(NO3)]n(NO3)n Adduct: Anticancer, and Antimicrobial Applications | 2023 | Inorganics 2023, 11, 395; dio. 10.3390/inorganics11100395 |
| Synthesis, X-ray Structure, Hirshfeld Surface Analysis and Antimicrobial Assessment of Tetranuclear s-Triazine Hydrazine Schiff Base Ligand | 2023 | Inorganics 2023, 11, 357; doi:10.3390/inorganics11090357. |
| X-ray Structures and Hirshfeld Studies of Two Dinuclear Cd(II) Complexes with a s-Triazine/Pyrazolo Ligand and Pesudohalides as a Linker | 2023 | Crystals 2023, 13, 1198; doi.10.3390/cryst13081198 |
| Synthesis, X-ray Structure and Hirshfeld Surface Analysis of Zn(II) and Cd(II) Complexes with s-Triazine Hydrazone Ligand | 2023 | Crystals 2023, 13, 1232; doi:10.3390/cryst13081232 |
| Novel Proton Exchange Membranes Based on Sulfonated Poly(acrylonitrile-co-glycidyl methacrylate)/ Poly(vinyl chloride) Composite | 2023 | Sustainability 2023, 15, 11166; doi. 10.3390/su151411166 |
| Supramolecular Structure and Antimicrobial Activity of Ni(II) Complexes with s-Triazine/Hydrazine Type Ligand | 2023 | Inorganics 2023, 11, 253; doi:10.3390/inorganics11060253 |
| A Novel Na(I) Coordination Complex with s-Triazine Pincer Ligand: Synthesis, X-ray Structure, Hirshfeld Analysis, and Antimicrobial Activity | 2023 | Crystals 2023, 13, 890; doi: 10.3390/cryst13060890 |
| Synthesis, X-ray Structure of Two Hexa-Coordinated Ni(II) Complexes with s-Triazine Hydrazine Schiff Base Ligand | 2023 | Inorganics 2023, 11, 222; doi: 10.3390/inorganics11050222 |
| Synthesis, Structure and Antimicrobial Activity of New Co(II) Complex with bis-Morpholino/Benzoimidazole-s-Triazine Ligand | 2023 | Inorganics 2023, 11, 278; doi.10.3390/inorganics11070278 |
| Synthesis, Characterizations, Antitumor and Antimicrobial Evaluations of Novel Mn(II) and Cu(II) Complexes with NNN-tridentate s-Triazine-Schiff base Ligand | 2023 | Inorganica Chimica Acta 2023, 555, 121586, doi.org/10.1016/j.ica.2023.121586 |
| A New 1D Ni (II) Coordination Polymer of s-Triazine Type Ligand and Thiocyanate as Linker via Unexpected Hydrolysis of 2,4-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine | 2023 | Inorganics 2023, 11(3), 135; doi.10.3390/inorganics11030135 |
| Synthesis, Structural Investigations, and Potential Antimicrobial and Anticancer Activity of Mononuclear Zn(II) and Cd(II) Complexes Decorated by Morpholine/Pyrazole s-Triazine Ligand | 2024 | Applied Organometallic Chemistry, 2024; 0:e7772; doi.org/10.1002/aoc.7772 |
| Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/ CDK2 inhibitors for halting breast cancer cells | 29-02-2024 | Frontiers in Chemistry |
| Bis(dimethylpyrazolyl)-aniline-s-triazine derivatives as efficient corrosion inhibitors for C-steel and computational studies | 12-03-2024 | Royal Soc.,Open Sci. |
| Synthesis, X-ray Structure, Cytotoxic, and Anti-Microbial Activities of Zn(II) Complexes with a Hydrazono s-Triazine Bearing Pyridyl Arm | 19-06-2024 | Inorganics |
| Synthesis of Co(II), Mn(II), and Ni(II) complexes with 4-(4,6-bis (3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazin-2-yl)morpholine; X-ray structure, Hirshfeld, AIM, and biological studies | 08-07-2024 | Inorganica Chimica Acta |
| Experimental and Computational Anticorrosion Behaviors of Pyrazole s Triazine/anilino-morpholino Derivatives for Steel in Acidic Solutions | 11-07-2024 | ACS Omega |
| Homoleptic Co(II) and Ni(II) complexes with promising anticancer and antimicrobial activities; Synthesis, X-ray structure, and DFT studies | 24-08-2024 | Journal of Molecular Structure |
| Novel Spirooxindole-Triazole Derivatives: Unveiling [3+2] Cycloaddition Reactivity Through Molecular Electron Density Theory and Investigating Their Potential Cytotoxicity Against HepG2 and MDA-MB-231 Cell Lines | 23-09-2024 | Frontiers in Chemistry, section Organic Chemistry. doi: 10.3389/fchem.2024.1460384 |
| Structural and Biological Comparative Studies on M(II)-Complexes (M = Co, Mn, Cu, Ni, Zn) of Hydrazone-s-Triazine Ligand Bearing Pyridyl Arm | 14-10-2024 | Inorganics 2024, 12, 268; doi: 10.3390/inorganics12100268 |
| A New Bromo-Mn(II) Complex with 1,3,5-Triazine derivative: Synthesis, Crystal Structure, DFT and Biological Studies | 28-10-2024 | Inorganics 2024, 12(11), 284; doi: 10.3390/inorganics12110284. |
| Title | From | To | Note |
|---|---|---|---|
| Head of Scientific Research and Innovation Unit at College of Medicine | 08-09-2024 | ||
| Member of the Scientific Research and Innovation Committee at DAU | 12-09-2024 | ||
| Head of the Entrepreneurship& Innovation and Knowledge transfer Center at DAU | 12-09-2024 |
| Title | Donor | Date |
|---|---|---|
| Unilever Sustainable Living Plan Prize for the best Article | 2016 | |
| Award of Excellence in Scientific Publishing from Quality Authority (CIQAP) Egypt | 2012 | |
| Prize of Administrative Excellence Alexandria University | 2012 | |
| Medal for Distinguish Scientific Publication in Chemistry, Alexandria University | 2010 | |
| Nominated to submit a proposal for Noble Prize in Chemistry | 2003 | |
| Alexandria University Award for Science | 1999 |